DETAILED NOTES ON LAUGHING GAS

The last proposed system of RBC vasodilation from the existence of nitrite could be the reduction of nitrite to NO by Hb. Brooks very first researched the nitrite Hb conversation in 1937 and this perform was afterwards extended by Doyle in 1981 (Brooks, 1937; Doyle et al., 1981). Nitrite reacts with deoxygenated Hb to sort metHb and NO (Brooks, 193